This paper describes the main functionalities of an integrated framework to model the interactions between land use, climate, and hydrology along with stakeholders’ negotiation. Its novelty lies in the combination of individual-based and spatially distributed models within the Socio-Hydrology paradigm to capture the complexity and uncertainty inherent to these systems. It encompasses a land-use/land-cover cellular automata model, an agent-based model used for automated stakeholders’ negotiation, and the hydrological MIKE SHE/MIKE 11 model, which are linked and can be accessed through a web-based interface. It enables users to run simulations to explore a wide range of scenarios related to land development and water resource management while considering the reciprocal influence of human and natural systems. This framework was developed with the involvement of key stakeholders from the initial design stage to the final demonstration and validation.